Most grand slam home runs in a Major League Baseball career

- Who
- Alex Rodriguez
- What
- 25 total number
- Where
- United States
- When
- 2015
The Major League Baseball (MLB) record for most career grand slam home runs (a home run hit with the bases loaded) is 25, set by Alex Rodriguez (USA) while playing for the Seattle Mariners, Texas Rangers and New York Yankees (USA) since 1994.
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